“It would appear so.” “At least we may accept it as a working hypothesis. We will suppose, then, that something was burned in each case which produced an atmosphere causing strange toxic effects. Very good. In the first instance — that of the Tregennis family — this substance was placed in the fire. Now the window was shut, but the fire would naturally carry fumes to some extent up the chimney. Hence one would expect the effects of the poison to be less than in the second case, where there was less escape for the vapour. The result seems to indicate that it was so, since in the first case only the woman, who had presumably the more sensitive organism, was killed, the others exhibiting that temporary or permanent lunacy which is evidently the first effect of the drug. In the second case th